Bio Remodelling

Bio-remodelling injections for the skin.

Profhilo Bio remodelling
The 5 Key Injecting Points of Bio Remodelling

What Is Bio-Remodelling?

Bio-remodelling is a skin quality treatment designed to support the skin’s natural repair and regenerative functions at a cellular level. It focuses on improving the biological environment within the skin, rather than altering facial shape or structure.

This approach works within the dermal and subdermal layers of the skin, where collagen fibres, elastin fibres, fibroblasts and extracellular matrix components are located. These structures are responsible for skin strength, firmness, elasticity, and hydration balance.

Rather than creating volume or contour changes, bio-remodelling focuses on:

  • Supporting fibroblast activity (cells responsible for collagen and elastin production)
  • Improving hydration retention within the skin
  • Enhancing overall skin resilience and integrity
  • Supporting ageing skin at a structural level

This makes it suitable for patients who are concerned with skin quality deterioration rather than volume loss.

Physiological Effects on the Skin

As part of the natural ageing process, several physiological changes occur in the skin, including:

  • Reduction in collagen density
  • Fragmentation of elastin fibres
  • Decreased fibroblast activity
  • Thinning of the dermis
  • Reduced hyaluronic balance and water retention
  • Slower cellular turnover

Bio-remodelling treatments are designed to influence the dermal microenvironment, supporting tissue repair mechanisms and encouraging improved cellular function over time.

The goal is to enhance:

  • Skin firmness
  • Elastic recoil
  • Structural support
  • Surface smoothness
  • Hydration balance

These effects develop progressively rather than instantly, as they rely on biological response rather than physical filling.

Difference Between Bio-Remodelling and Skin Conditioning Procedures

Bio-remodelling is distinct from many traditional cosmetic skin procedures because it focuses on global tissue quality rather than isolated areas of concern.

Key medical distinctions include:

  • Supports both collagen and elastin activity, rather than collagen alone
  • Focuses on dermal support rather than epidermal exfoliation
  • Designed to treat widespread skin laxity rather than focal volume loss
  • Works across interconnected tissue planes for more uniform skin quality

By addressing both elastin and collagen structures, this method targets two of the primary structural proteins responsible for skin ageing.

Treatment Areas and Anatomical Considerations

Bio-remodelling may be considered in areas of the body where skin thinning, laxity or texture change is commonly observed, including:

  • Face (mid-face, lower face and perioral region)
  • Neck (submental and anterior cervical regions)
  • Décolletage (upper chest area)
  • Hands (dorsal surfaces)

Treatment planning involves a detailed assessment of:

  • Skin thickness
  • Skin elasticity
  • Underlying vascular anatomy
  • Nerve pathways
  • Previous surgical or procedural history
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